Which antibiotic covers CA-MRSA?

Prepare for the Antibacterials (ABX) Exam. Study with flashcards and multiple-choice questions, each question comes with hints and explanations. Get ready to ace your test!

Multiple Choice

Which antibiotic covers CA-MRSA?

Explanation:
Coverage of CA-MRSA hinges on using an antibiotic with activity against MRSA. MRSA strains resist most beta-lactams because of the mecA gene, so reliable treatment relies on agents that retain MRSA activity. In community-associated MRSA, you’ll often use non–beta-lactams such as trimethoprim-sulfamethoxazole, doxycycline, or clindamycin (checking the D-test for inducible resistance), and for more serious infections, IV options like vancomycin, linezolid, daptomycin, or ceftaroline. The option listed reflects an idea about the target of therapy rather than naming a specific MRSA-active drug, which is why it aligns with the concept of needing MRSA coverage. The other choices point to different organisms or non-antibiotic entities and would not represent agents or targets aligned with MRSA coverage. In short, treating CA-MRSA requires an antibiotic with proven MRSA activity, and CA-MRSA represents the organism that would demand that kind of coverage.

Coverage of CA-MRSA hinges on using an antibiotic with activity against MRSA. MRSA strains resist most beta-lactams because of the mecA gene, so reliable treatment relies on agents that retain MRSA activity. In community-associated MRSA, you’ll often use non–beta-lactams such as trimethoprim-sulfamethoxazole, doxycycline, or clindamycin (checking the D-test for inducible resistance), and for more serious infections, IV options like vancomycin, linezolid, daptomycin, or ceftaroline. The option listed reflects an idea about the target of therapy rather than naming a specific MRSA-active drug, which is why it aligns with the concept of needing MRSA coverage. The other choices point to different organisms or non-antibiotic entities and would not represent agents or targets aligned with MRSA coverage. In short, treating CA-MRSA requires an antibiotic with proven MRSA activity, and CA-MRSA represents the organism that would demand that kind of coverage.

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