Which drug is commonly associated with metallic taste and glossitis?

Which drug is commonly associated with metallic taste and glossitis?

• A. Metronidazole
• B. Daptomycin
• C. Nitrofurantoin
• D. Linezolid

Answer: (A)

Metronidazole is commonly associated with metallic taste and glossitis because dysgeusia and tongue/mucosal irritation are well-documented adverse effects of this nitroimidazole antibiotic. Patients often report a persistent metallic or bitter taste, and the tongue can become sore or inflamed. The other drugs tend to cause different problem patterns: daptomycin is linked mainly to muscle toxicity and CPK elevation; nitrofurantoin can cause pulmonary or hepatic toxicity and GI upset; linezolid can lead to bone marrow suppression or neuropathies and interactions like serotonin syndrome. So metronidazole best matches the described symptoms.

Metronidazole is commonly associated with metallic taste and glossitis because dysgeusia and tongue/mucosal irritation are well-documented adverse effects of this nitroimidazole antibiotic. Patients often report a persistent metallic or bitter taste, and the tongue can become sore or inflamed. The other drugs tend to cause different problem patterns: daptomycin is linked mainly to muscle toxicity and CPK elevation; nitrofurantoin can cause pulmonary or hepatic toxicity and GI upset; linezolid can lead to bone marrow suppression or neuropathies and interactions like serotonin syndrome. So metronidazole best matches the described symptoms.